Alec Pierce vs Brandon Aiyuk: The Full Breakdown
This is a genuine coin flip on paper. Alec Pierce finished the 2025 season at 10.7 PPG over 15 games with the Indianapolis Colts, while Brandon Aiyuk clocked in at 11.8 across 13 appearances for the San Francisco 49ers. A 1.1-point gap means any given week could go either way.
With a margin this thin, season averages are not the deciding factor. Weekly variables like opponent defense, game script, and injury status carry more weight than a fraction of a PPG. The right start in Week 6 might be the wrong start in Week 14.
Both are workload receivers with similar target shares. Alec Pierce turned 84 targets into 1003 yards and 6 touchdowns, while Brandon Aiyuk converted 82 looks into 762 yards and 5 scores. When target volume is this close, game script and defensive matchup typically decide the weekly winner.
One scheduling note: Alec Pierce is off Week 13 and Brandon Aiyuk Week 9. If these two are on your roster, you will need a fill-in wide receiver for both weeks. DraftCall flags bye conflicts so you can plan ahead rather than panic on waivers.
