Amari Cooper vs Khalil Shakir: The Full Breakdown
If you are choosing between Amari Cooper and Khalil Shakir for your lineup, you are not alone. Amari Cooper finished the 2025 season at 11.2 PPG for the Buffalo Bills (16 games), and Khalil Shakir averaged 8.1 for the Buffalo Bills (16 games).
That 3.1-point weekly advantage for Amari Cooper is meaningful but not automatic. Fantasy football is a week-to-week sport, and the answer to "who should I start" often changes based on opponent, recent form, and game environment. Season averages set the baseline; weekly context makes the call.
Both are workload receivers with similar target shares. Amari Cooper turned 95 targets into 782 yards and 4 touchdowns, while Khalil Shakir converted 95 looks into 719 yards and 4 scores. When target volume is this close, game script and defensive matchup typically decide the weekly winner.
One scheduling note: Amari Cooper is off Week 12 and Khalil Shakir Week 7. If these two are on your roster, you will need a fill-in wide receiver for both weeks. DraftCall flags bye conflicts so you can plan ahead rather than panic on waivers.
