Brandon Aiyuk vs Darnell Mooney: The Full Breakdown
Two wide receivers who will land on plenty of the same rosters in 2026. Brandon Aiyuk (San Francisco 49ers) finished the 2025 season averaging 11.8 fantasy points per game in 13 games. Darnell Mooney (Atlanta Falcons) came in at 7.5 PPG over 15 games. The gap is real but not insurmountable with the right matchup.
Brandon Aiyuk carries a 4.3-point PPG advantage from the 2025 season. That baseline matters, but it is one input among several. Matchup difficulty, scoring trends, and injury reports move the needle week to week, which is why the best answer changes depending on when you are asking.
Both are workload receivers with similar target shares. Brandon Aiyuk turned 82 targets into 762 yards and 5 touchdowns, while Darnell Mooney converted 78 looks into 612 yards and 3 scores. When target volume is this close, game script and defensive matchup typically decide the weekly winner.
One scheduling note: Brandon Aiyuk is off Week 9 and Darnell Mooney Week 12. If these two are on your roster, you will need a fill-in wide receiver for both weeks. DraftCall flags bye conflicts so you can plan ahead rather than panic on waivers.
