Brandon Aiyuk vs DJ Moore: The Full Breakdown
Deciding between Brandon Aiyuk and DJ Moore is a common lineup dilemma for fantasy managers. The San Francisco 49ers wide receiver put up 11.8 PPG in 2025 over 13 games; DJ Moore of the Chicago Bears averaged 8.7 in 17. A 3.1-point margin that could shift on any given week.
The per-game difference of 3.1 points favors Brandon Aiyuk, though savvy managers know that gap can shrink or widen depending on the weekly slate. Defensive matchup, recent scoring trends, and health status all shift the calculus from one wide receiver to the other.
Both are workload receivers with similar target shares. Brandon Aiyuk turned 82 targets into 762 yards and 5 touchdowns, while DJ Moore converted 85 looks into 682 yards and 6 scores. When target volume is this close, game script and defensive matchup typically decide the weekly winner.
One scheduling note: Brandon Aiyuk is off Week 9 and DJ Moore Week 10. If these two are on your roster, you will need a fill-in wide receiver for both weeks. DraftCall flags bye conflicts so you can plan ahead rather than panic on waivers.
