Brandon Aiyuk vs Jakobi Meyers: The Full Breakdown
Two wide receivers who will land on plenty of the same rosters in 2026. Brandon Aiyuk (San Francisco 49ers) finished the 2025 season averaging 11.8 fantasy points per game in 13 games. Jakobi Meyers (Jacksonville Jaguars) came in at 8.6 PPG over 16 games. The gap is real but not insurmountable with the right matchup.
Brandon Aiyuk carries a 3.2-point PPG advantage from the 2025 season. That baseline matters, but it is one input among several. Matchup difficulty, scoring trends, and injury reports move the needle week to week, which is why the best answer changes depending on when you are asking.
Target volume is the story here. Jakobi Meyers saw 110 targets in 2025, while Brandon Aiyuk drew 82. That workload gap usually translates into a higher weekly floor for Jakobi Meyers, even in weeks where Brandon Aiyuk posts the bigger ceiling game. Consistency-minded managers lean toward target share; boom-bust managers chase the upside.
Brandon Aiyuk has his bye in Week 9, and Jakobi Meyers rests in Week 7. Managers rostering both need waiver wire depth at wide receiver for those two weeks, and that is exactly the kind of planning DraftCall's matchup engine surfaces automatically so you are not scrambling on a Sunday morning.
