Brandon Aiyuk vs Kayshon Boutte: The Full Breakdown
Deciding between Brandon Aiyuk and Kayshon Boutte is a common lineup dilemma for fantasy managers. The San Francisco 49ers wide receiver put up 11.8 PPG in 2025 over 13 games; Kayshon Boutte of the New England Patriots averaged 7.7 in 14. A 4.1-point margin that could shift on any given week.
The per-game difference of 4.1 points favors Brandon Aiyuk, though savvy managers know that gap can shrink or widen depending on the weekly slate. Defensive matchup, recent scoring trends, and health status all shift the calculus from one wide receiver to the other.
Target volume is the story here. Brandon Aiyuk saw 82 targets in 2025, while Kayshon Boutte drew 46. That workload gap usually translates into a higher weekly floor for Brandon Aiyuk, even in weeks where Kayshon Boutte posts the bigger ceiling game. Consistency-minded managers lean toward target share; boom-bust managers chase the upside.
One scheduling note: Brandon Aiyuk is off Week 9 and Kayshon Boutte Week 11. If these two are on your roster, you will need a fill-in wide receiver for both weeks. DraftCall flags bye conflicts so you can plan ahead rather than panic on waivers.
