Head to Head

Updated June 3, 2026 from live stats

Brandon Aiyuk vs Kyren WilliamsWho should you start in 2026 fantasy football?

Kyren Williams is the better fantasy start for 2026, averaging 14.4 PPG to Brandon Aiyuk's 11.8 in 2025. Full head to head breakdown below.

The Bottom Line

Kyren Williams is the better fantasy play this season.

Cross-position decisions depend on league format. In half-PPR, Kyren Williams (14.4 PPG) is the higher-floor play. Brandon Aiyuk (11.8 PPG) could win a specific week on touchdown variance. For FLEX spots, lean toward the player with the softer defensive matchup that week rather than defaulting to season averages.

Moderate confidence: stats favor the leader, but matchup variance could flip this weekly.

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WRSan Francisco 49ers#99

Brandon Aiyuk

PPG

11.8

Games

Rec

Rec Yds

762

Rec TDs

Targets

Bye

Week 9

RBLos Angeles Rams#11PPG LEADER

Kyren Williams

PPG

14.4

Games

Rush Yds

1,252

Rush TDs

Rec

Rec Yds

281

Bye

Week 11

The Edge Chart

Brandon Aiyuk

Kyren Williams

Head to Head

11.8 PPG14.4 PPG

13 GP17 GP

Bye: Week 9Bye: Week 11

Fantasy Tiers

Brandon Aiyuk: Tier 5 (Deep League) WR (ranked #99 at the position). Kyren Williams: Tier 2 (Strong Starter) RB (ranked #11 at the position). Comparing across positions, raw PPG is less useful than positional scarcity. A Tier 5 (Deep League) WR is harder to replace on waivers than a Tier 2 (Strong Starter) RB in most league formats.

Brandon Aiyuk vs Kyren Williams: The Full Breakdown

Comparing Brandon Aiyuk (WR, San Francisco 49ers) against Kyren Williams (RB, Los Angeles Rams) means weighing two different roles in your fantasy lineup. Brandon Aiyuk averaged 11.8 PPG in 2025 over 13 games, while Kyren Williams posted 14.4 PPG across 17 games.

Cross-position FLEX decisions cannot be made on PPG alone. Positional scarcity, matchup quality, floor versus ceiling, and league scoring format all shift the answer. A 14 PPG tight end in a thin TE week is often worth more than a 16 PPG receiver in a deep WR week, because the opportunity cost on the waiver wire is wildly different.

DraftCall's AI engine weighs all of these signals and returns a verdict with clear reasoning, so you are not cross-referencing four different rankings tabs on a Sunday morning.

Brandon Aiyuk has his bye in Week 9, Kyren Williams in Week 11. Plan your FLEX rotation around those weeks, especially if either player is anchoring your roster.

Trade Value + Dynasty Outlook

Both are in a similar trade value range. A straight swap would be fair in most leagues, with the tiebreaker going to whichever manager values schedule or bye week more. Dynasty outlook: Brandon Aiyuk (age 27) is in the middle of his productive window. Stable dynasty value. Kyren Williams (age 25) has not yet hit the RB cliff. High dynasty ceiling if volume holds.

Did You Know?

•Kyren Williams outscored Brandon Aiyuk by a projected 44 total fantasy points over a full 17-game season.
•Kyren Williams played 17 games in 2025 compared to Brandon Aiyuk's 13. That durability gap means Kyren Williams contributed more total fantasy points even before you look at per-game averages.
•Kyren Williams scored 13 total touchdowns in 2025 (0.8 per game), making him one of the more reliable scoring options at running back.
•Brandon Aiyuk saw 82 targets in 2025. Target volume is the single strongest predictor of weekly PPR production at the wide receiver position.

Detailed Stat Breakdown

Brandon Aiyuk vs Kyren Williams: 2025 fantasy football stat comparison in the half-PPR scoring format.
Stat	Brandon Aiyuk	Kyren Williams
PPG (Half-PPR)	11.8	14.4
Games Played	13	17
Total Fantasy Pts (est.)	153	245
Rushing Yards	0	1,252
Rush Yds/Game	0.0	73.6
Rushing TDs	0	10
Receptions	58	36
Receiving Yards	762	281
Targets	82	50
Total TDs	5	13
Age	-	25
Experience	-	3 yrs
Bye Week	Week 9	Week 11

Summary

Kyren Williams outscored Brandon Aiyuk by 2.6 PPG in 2025 (14.4 to 11.8). That production gap is the baseline, but weekly context shifts the answer. DraftCall analyzes matchup difficulty, scoring trends, and health data to deliver a clear start or sit recommendation backed by real reasoning.

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Frequently Asked Questions

Should I start Brandon Aiyuk or Kyren Williams in fantasy football?▾

Based on 2025 season averages, Kyren Williams has the edge at 14.4 PPG compared to Brandon Aiyuk's 11.8 PPG. However, the best start depends on weekly matchup, recent form, and injury status. DraftCall's app provides real-time AI-powered verdicts that factor in all of these variables.

How many fantasy points did Brandon Aiyuk and Kyren Williams average in 2025?▾

Brandon Aiyuk averaged 11.8 fantasy points per game (half-PPR) across 13 games in 2025. Kyren Williams averaged 14.4 PPG over 17 games. That is a difference of 2.6 points per game.

When are Brandon Aiyuk and Kyren Williams's bye weeks in 2026?▾

Brandon Aiyuk (SF) has a bye in Week 9, and Kyren Williams (LAR) has a bye in Week 11. Plan your roster accordingly if you are carrying both players.