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Head to Head

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Brandon Aiyuk vs Mark AndrewsWho should you start in 2026 fantasy football?

Brandon Aiyuk is the better fantasy start for 2026, averaging 11.8 PPG to Mark Andrews's 6.3 in 2025. Full head to head breakdown below.

The Bottom Line

Brandon Aiyuk is the better fantasy play this season.

Cross-position decisions depend on league format. In half-PPR, Brandon Aiyuk (11.8 PPG) is the higher-floor play. Mark Andrews (6.3 PPG) could win a specific week on touchdown variance. For FLEX spots, lean toward the player with the softer defensive matchup that week rather than defaulting to season averages.

High confidence: stats strongly favor the leader, and the gap is unlikely to close on matchup alone.

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WRSan Francisco 49ers#99PPG LEADER
Brandon Aiyuk
PPG
11.8
Games
13
Rec
58
Rec Yds
762
Rec TDs
5
Targets
82
Bye
Week 9
TEBaltimore Ravens#27
Mark Andrews
PPG
6.3
Games
17
Rec
48
Rec Yds
422
Rec TDs
5
Targets
70
Bye
Week 13

The Edge Chart

VolumeEfficiencyTD UpsideFloorCeilingDurability
Brandon Aiyuk
Mark Andrews

Head to Head

11.8 PPG6.3 PPG
13 GP17 GP
Bye: Week 9Bye: Week 13

Fantasy Tiers

Brandon Aiyuk: Tier 5 (Deep League) WR (ranked #99 at the position). Mark Andrews: Tier 4 (Bench/Bye Fill) TE (ranked #27 at the position). Comparing across positions, raw PPG is less useful than positional scarcity. A Tier 5 (Deep League) WR is harder to replace on waivers than a Tier 4 (Bench/Bye Fill) TE in most league formats.

Brandon Aiyuk vs Mark Andrews: The Full Breakdown

Comparing Brandon Aiyuk (WR, San Francisco 49ers) against Mark Andrews (TE, Baltimore Ravens) means weighing two different roles in your fantasy lineup. Brandon Aiyuk averaged 11.8 PPG in 2025 over 13 games, while Mark Andrews posted 6.3 PPG across 17 games.

Cross-position FLEX decisions cannot be made on PPG alone. Positional scarcity, matchup quality, floor versus ceiling, and league scoring format all shift the answer. A 14 PPG tight end in a thin TE week is often worth more than a 16 PPG receiver in a deep WR week, because the opportunity cost on the waiver wire is wildly different.

DraftCall's AI engine weighs all of these signals and returns a verdict with clear reasoning, so you are not cross-referencing four different rankings tabs on a Sunday morning.

Brandon Aiyuk has his bye in Week 9, Mark Andrews in Week 13. Plan your FLEX rotation around those weeks, especially if either player is anchoring your roster.

Trade Value + Dynasty Outlook

If you can acquire Brandon Aiyuk at a discount because your league-mates undervalue wide receiver production, do it. Mark Andrews is a reasonable sell-high candidate if his recent games have spiked above his season average. Dynasty outlook: Brandon Aiyuk (age 27) is in the middle of his productive window. Stable dynasty value. Mark Andrews (age 30) is in the later years of production. Still a redraft asset, but dynasty value is declining.

Did You Know?

  • Brandon Aiyuk outscored Mark Andrews by a projected 94 total fantasy points over a full 17-game season.
  • Mark Andrews played 17 games in 2025 compared to Brandon Aiyuk's 13. That durability gap means Mark Andrews contributed more total fantasy points even before you look at per-game averages.
  • Mark Andrews scored 6 total touchdowns in 2025 (0.4 per game), making him one of the more reliable scoring options at tight end.
  • Brandon Aiyuk saw 82 targets in 2025. Target volume is the single strongest predictor of weekly PPR production at the wide receiver position.

Detailed Stat Breakdown

Brandon Aiyuk vs Mark Andrews: 2025 fantasy football stat comparison in the half-PPR scoring format.
StatBrandon AiyukMark Andrews
PPG (Half-PPR)11.86.3
Games Played1317
Total Fantasy Pts (est.)153107
Receptions5848
Rec/Game4.52.8
Receiving Yards762422
Rec Yds/Game58.624.8
Receiving TDs55
Targets8270
Target Share/Game6.34.1
Age-30
Experience-7 yrs
Bye WeekWeek 9Week 13

Summary

Brandon Aiyuk outscored Mark Andrews by 5.5 PPG in 2025 (11.8 to 6.3). That production gap is the baseline, but weekly context shifts the answer. DraftCall analyzes matchup difficulty, scoring trends, and health data to deliver a clear start or sit recommendation backed by real reasoning.

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Frequently Asked Questions

Should I start Brandon Aiyuk or Mark Andrews in fantasy football?

Based on 2025 season averages, Brandon Aiyuk has the edge at 11.8 PPG compared to Mark Andrews's 6.3 PPG. However, the best start depends on weekly matchup, recent form, and injury status. DraftCall's app provides real-time AI-powered verdicts that factor in all of these variables.

How many fantasy points did Brandon Aiyuk and Mark Andrews average in 2025?

Brandon Aiyuk averaged 11.8 fantasy points per game (half-PPR) across 13 games in 2025. Mark Andrews averaged 6.3 PPG over 17 games. That is a difference of 5.5 points per game.

When are Brandon Aiyuk and Mark Andrews's bye weeks in 2026?

Brandon Aiyuk (SF) has a bye in Week 9, and Mark Andrews (BAL) has a bye in Week 13. Plan your roster accordingly if you are carrying both players.

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