Brandon Aiyuk vs Michael Pittman: The Full Breakdown
Deciding between Brandon Aiyuk and Michael Pittman is a common lineup dilemma for fantasy managers. The San Francisco 49ers wide receiver put up 11.8 PPG in 2025 over 13 games; Michael Pittman of the Indianapolis Colts averaged 9.6 in 17. A 2.2-point margin that could shift on any given week.
The per-game difference of 2.2 points favors Brandon Aiyuk, though savvy managers know that gap can shrink or widen depending on the weekly slate. Defensive matchup, recent scoring trends, and health status all shift the calculus from one wide receiver to the other.
Target volume is the story here. Michael Pittman saw 111 targets in 2025, while Brandon Aiyuk drew 82. That workload gap usually translates into a higher weekly floor for Michael Pittman, even in weeks where Brandon Aiyuk posts the bigger ceiling game. Consistency-minded managers lean toward target share; boom-bust managers chase the upside.
Bye weeks matter for roster construction: Brandon Aiyuk sits Week 9 while Michael Pittman is off Week 13. If you are deciding between the two as a season-long roster hold, the staggered byes actually work in your favor.
