Brock Purdy vs Michael Penix: Who Should You Start?
There is a real production gap between these two quarterbacks. Brock Purdy (San Francisco 49ers) averaged 20.8 PPG over 9 games in 2025, outscoring Michael Penix (Atlanta Falcons, 13.7 PPG) by 7.1 points per week. That separation would need a significant matchup swing to overcome.
Brock Purdy carries a 7.1-point PPG advantage from the 2025 season. That baseline matters, but it is one input among several. Matchup difficulty, scoring trends, and injury reports move the needle week to week, which is why the best answer changes depending on when you are asking.
Both lean on arm talent and offensive scheme as traditional pocket passers. Brock Purdy threw for 2167 yards and 20 touchdowns, while Michael Penix posted 1982 yards and 9 scores. Volume, red zone efficiency, and game script are the key week-to-week differentiators when neither carries rushing upside.
One scheduling note: Brock Purdy is off Week 9 and Michael Penix Week 12. If these two are on your roster, you will need a fill-in quarterback for both weeks. DraftCall flags bye conflicts so you can plan ahead rather than panic on waivers.