Christian McCaffrey vs Jonathan Taylor: Who Should You Start?
Deciding between Christian McCaffrey and Jonathan Taylor is a common lineup dilemma for fantasy managers. The San Francisco 49ers running back put up 21.5 PPG in 2025 over 17 games; Jonathan Taylor of the Indianapolis Colts averaged 20.0 in 17. A 1.5-point margin that could shift on any given week.
The per-game difference of 1.5 points favors Christian McCaffrey, though savvy managers know that gap can shrink or widen depending on the weekly slate. Defensive matchup, recent scoring trends, and health status all shift the calculus from one running back to the other.
Both are three-down backs with real passing-game roles. Christian McCaffrey caught 102 balls for 924 yards, and Jonathan Taylor hauled in 46 for 378. That receiving workload gives them high PPR floors even in games where the ground attack gets stuffed, and it is why both stay on the field in obvious passing situations.
One scheduling note: Christian McCaffrey is off Week 9 and Jonathan Taylor Week 14. If these two are on your roster, you will need a fill-in running back for both weeks. DraftCall flags bye conflicts so you can plan ahead rather than panic on waivers.