Dameon Pierce vs Omarion Hampton: The Full Breakdown
There is a real production gap between these two running backs. Omarion Hampton (Los Angeles Chargers) averaged 13.3 PPG over 9 games in 2025, outscoring Dameon Pierce (Houston Texans, 6.4 PPG) by 6.9 points per week. That separation would need a significant matchup swing to overcome.
A 6.9-PPG gap gives Omarion Hampton the edge on paper, but paper does not account for Thursday night matchups, weather games, or a star defender returning from injury. The real question is not who was better in 2025, but who is the better start this specific week.
Both profile as early-down workhorses. Dameon Pierce ran for 342 yards and 2 touchdowns; Omarion Hampton posted 545 and 4. Goal-line share, red zone touches, and which team is favored are usually the tiebreaker when neither back offers passing-game volume.
One scheduling note: Dameon Pierce is off Week 14 and Omarion Hampton Week 7. If these two are on your roster, you will need a fill-in running back for both weeks. DraftCall flags bye conflicts so you can plan ahead rather than panic on waivers.
