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Head to Head

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Derrick Henry vs Samaje PerineWho should you start in 2026 fantasy football?

Derrick Henry is the better fantasy start for 2026, averaging 16.0 PPG to Samaje Perine's 6.5 in 2025. Full head to head breakdown below.

The Bottom Line

Derrick Henry is the better fantasy play this season.

Derrick Henry is clearly the better fantasy option heading into 2026. With 16.0 PPG and 1,745 total yards in 2025, the production separation is too wide to overcome on matchup alone. Samaje Perine (6.5 PPG) is a hold, not a sell, but roster Derrick Henry as the starter and Samaje Perine as depth.

High confidence: stats strongly favor the leader, and the gap is unlikely to close on matchup alone.

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RBBaltimore Ravens#7PPG LEADER
Derrick Henry
PPG
16.0
Games
17
Rush Yds
1,595
Rush TDs
16
Rec
15
Rec Yds
150
Bye
Week 13
RBKansas City Chiefs#99
Samaje Perine
PPG
6.5
Games
15
Rush Yds
285
Rush TDs
2
Rec
24
Rec Yds
182
Bye
Week 6

The Edge Chart

VolumeEfficiencyTD UpsideFloorCeilingDurability
Derrick Henry
Samaje Perine

Head to Head

16.0 PPG6.5 PPG
17 GP15 GP
Bye: Week 13Bye: Week 6

Fantasy Tiers

Derrick Henry: Tier 2 (Strong Starter) RB (ranked #7 at the position). Samaje Perine: Tier 5 (Deep League) RB (ranked #99 at the position). Among the top 50 running backs this season, Derrick Henry is producing at 73% of elite pace and Samaje Perine at 30%. That ranking gap means Derrick Henry carries more trade value and a higher draft cost in 2026.

Derrick Henry vs Samaje Perine: The Full Breakdown

There is a real production gap between these two running backs. Derrick Henry (Baltimore Ravens) averaged 16.0 PPG over 17 games in 2025, outscoring Samaje Perine (Kansas City Chiefs, 6.5 PPG) by 9.5 points per week. That separation would need a significant matchup swing to overcome.

Derrick Henry carries a 9.5-point PPG advantage from the 2025 season. That baseline matters, but it is one input among several. Matchup difficulty, scoring trends, and injury reports move the needle week to week, which is why the best answer changes depending on when you are asking.

Both profile as early-down workhorses. Derrick Henry ran for 1595 yards and 16 touchdowns; Samaje Perine posted 285 and 2. Goal-line share, red zone touches, and which team is favored are usually the tiebreaker when neither back offers passing-game volume.

One scheduling note: Derrick Henry is off Week 13 and Samaje Perine Week 6. If these two are on your roster, you will need a fill-in running back for both weeks. DraftCall flags bye conflicts so you can plan ahead rather than panic on waivers.

Trade Value + Dynasty Outlook

If you can acquire Derrick Henry at a discount because your league-mates undervalue running back production, do it. Samaje Perine is a reasonable sell-high candidate if his recent games have spiked above his season average. Dynasty outlook: Derrick Henry (age 32, 9 years) is past the typical RB peak. Redraft value exceeds dynasty value. Samaje Perine (age 27) is approaching the age where RB production historically drops. Sell-high window is open.

Did You Know?

  • Derrick Henry outscored Samaje Perine by a projected 162 total fantasy points over a full 17-game season.
  • Derrick Henry played 17 games in 2025 compared to Samaje Perine's 15. That durability gap means Derrick Henry contributed more total fantasy points even before you look at per-game averages.
  • Derrick Henry scored 16 total touchdowns in 2025 (0.9 per game), making him one of the more reliable scoring options at running back.

Detailed Stat Breakdown

Derrick Henry vs Samaje Perine: 2025 fantasy football stat comparison in the half-PPR scoring format.
StatDerrick HenrySamaje Perine
PPG (Half-PPR)16.06.5
Games Played1715
Total Fantasy Pts (est.)27298
Rushing Yards1,595285
Rush Yds/Game93.819.0
Rushing TDs162
Receptions1524
Receiving Yards150182
Targets210
Total TDs163
Age32-
Experience9 yrs-
Bye WeekWeek 13Week 6

Summary

Based on 2025 production, Derrick Henry holds the PPG edge with solid output at 16.0 points per game. Samaje Perine averaged 6.5 PPG. Season averages are a starting point, not the final word. For a full AI analysis factoring matchup quality, recent form, injury impact, and game script, download DraftCall and get a verdict backed by real data.

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Frequently Asked Questions

Should I start Derrick Henry or Samaje Perine in fantasy football?

Based on 2025 season averages, Derrick Henry has the edge at 16.0 PPG compared to Samaje Perine's 6.5 PPG. However, the best start depends on weekly matchup, recent form, and injury status. DraftCall's app provides real-time AI-powered verdicts that factor in all of these variables.

How many fantasy points did Derrick Henry and Samaje Perine average in 2025?

Derrick Henry averaged 16.0 fantasy points per game (half-PPR) across 17 games in 2025. Samaje Perine averaged 6.5 PPG over 15 games. That is a difference of 9.5 points per game.

When are Derrick Henry and Samaje Perine's bye weeks in 2026?

Derrick Henry (BAL) has a bye in Week 13, and Samaje Perine (KC) has a bye in Week 6. Plan your roster accordingly if you are carrying both players.

Is Derrick Henry or Samaje Perine a better fantasy running back in 2026?

Derrick Henry outscored Samaje Perine by 9.5 PPG in 2025, which gives him the edge heading into 2026. For a week-by-week verdict, DraftCall's AI analyzes matchup quality and recent trends in real time.

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