Derrick Henry vs Zonovan Knight: Who Should You Start?
The numbers tell a clear story here. Derrick Henry put up 16.0 fantasy points per game for the Baltimore Ravens in 2025, while Zonovan Knight managed 6.8 across 12 games with the Arizona Cardinals. A 9.2-point weekly edge is substantial at the running back position.
A 9.2-PPG gap gives Derrick Henry the edge on paper, but paper does not account for Thursday night matchups, weather games, or a star defender returning from injury. The real question is not who was better in 2025, but who is the better start this specific week.
Both profile as early-down workhorses. Derrick Henry ran for 1595 yards and 16 touchdowns; Zonovan Knight posted 269 and 4. Goal-line share, red zone touches, and which team is favored are usually the tiebreaker when neither back offers passing-game volume.
Bye weeks matter for roster construction: Derrick Henry sits Week 14 while Zonovan Knight is off Week 11. If you are deciding between the two as a season-long roster hold, the staggered byes actually work in your favor.