Dylan Sampson vs TreVeyon Henderson: Who Should You Start?
There is a real production gap between these two running backs. TreVeyon Henderson (New England Patriots) averaged 11.1 PPG over 17 games in 2025, outscoring Dylan Sampson (Cleveland Browns, 4.7 PPG) by 6.4 points per week. That separation would need a significant matchup swing to overcome.
The per-game difference of 6.4 points favors TreVeyon Henderson, though savvy managers know that gap can shrink or widen depending on the weekly slate. Defensive matchup, recent scoring trends, and health status all shift the calculus from one running back to the other.
Both profile as early-down workhorses. Dylan Sampson ran for 175 yards and undefined touchdowns; TreVeyon Henderson posted 911 and 9. Goal-line share, red zone touches, and which team is favored are usually the tiebreaker when neither back offers passing-game volume.
One scheduling note: Dylan Sampson is off Week 10 and TreVeyon Henderson Week 14. If these two are on your roster, you will need a fill-in running back for both weeks. DraftCall flags bye conflicts so you can plan ahead rather than panic on waivers.
