Isiah Pacheco vs Omarion Hampton: Who Should You Start?
The numbers tell a clear story here. Omarion Hampton put up 13.3 fantasy points per game for the Los Angeles Chargers in 2025, while Isiah Pacheco managed 6.0 across 13 games with the Detroit Lions. A 7.3-point weekly edge is substantial at the running back position.
That 7.3-point weekly advantage for Omarion Hampton is meaningful but not automatic. Fantasy football is a week-to-week sport, and the answer to "who should I start" often changes based on opponent, recent form, and game environment. Season averages set the baseline; weekly context makes the call.
Both profile as early-down workhorses. Isiah Pacheco ran for 462 yards and 1 touchdowns; Omarion Hampton posted 545 and 4. Goal-line share, red zone touches, and which team is favored are usually the tiebreaker when neither back offers passing-game volume.
Both share a Week 5 bye, which matters for roster construction. If you are stacking running backs this deep on your bench, plan your replacement running back early.
