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Jacoby Brissett vs Patrick Mahomes

Fantasy Football Comparison for the 2026 NFL Season

QBArizona Cardinals
Jacoby Brissett
PPG
16.8
Games
14
Pass Yds
3,366
Pass TDs
23
Rush Yds
168
Rush TDs
1
Bye
Week 11
QBKansas City ChiefsPPG LEADER
Patrick Mahomes
PPG
21.2
Games
14
Pass Yds
3,587
Pass TDs
22
Rush Yds
422
Rush TDs
5
Bye
Week 6

Head to Head

16.8 PPG21.2 PPG
14 GP14 GP
Bye: Week 11Bye: Week 6

Jacoby Brissett vs Patrick Mahomes: Who Should You Start?

Jacoby Brissett and Patrick Mahomes are both viable fantasy quarterbacks heading into 2026, but their 2025 production tells two different stories. Jacoby Brissett averaged 16.8 PPG across 14 games with the Arizona Cardinals, while Patrick Mahomes posted 21.2 PPG in 14 appearances for the Kansas City Chiefs.

A 4.4-PPG gap gives Patrick Mahomes the edge on paper, but paper does not account for Thursday night matchups, weather games, or a star defender returning from injury. The real question is not who was better in 2025, but who is the better start this specific week.

Patrick Mahomes offers meaningful rushing upside with 422 yards on the ground in 2025, which separates his floor from a pocket passer like Jacoby Brissett (3366 passing yards, 23 touchdowns). In games where the passing matchup looks ugly, that rushing production can be the entire difference on a start/sit call.

One scheduling note: Jacoby Brissett is off Week 11 and Patrick Mahomes Week 6. If these two are on your roster, you will need a fill-in quarterback for both weeks. DraftCall flags bye conflicts so you can plan ahead rather than panic on waivers.

The Bottom Line

Patrick Mahomes outscored Jacoby Brissett by 4.4 PPG in 2025 (21.2 to 16.8). That production gap is the baseline, but weekly context shifts the answer. DraftCall analyzes matchup difficulty, scoring trends, and health data to deliver a clear start or sit recommendation backed by real reasoning.

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Frequently Asked Questions

Should I start Jacoby Brissett or Patrick Mahomes in fantasy football?

Based on 2025 season averages, Patrick Mahomes has the edge at 21.2 PPG compared to Jacoby Brissett's 16.8 PPG. However, the best start depends on weekly matchup, recent form, and injury status. DraftCall's app provides real-time AI-powered verdicts that factor in all of these variables.

How many fantasy points did Jacoby Brissett and Patrick Mahomes average in 2025?

Jacoby Brissett averaged 16.8 fantasy points per game (half-PPR) across 14 games in 2025. Patrick Mahomes averaged 21.2 PPG over 14 games. That is a difference of 4.4 points per game.

When are Jacoby Brissett and Patrick Mahomes's bye weeks in 2026?

Jacoby Brissett (ARI) has a bye in Week 11, and Patrick Mahomes (KC) has a bye in Week 6. Plan your roster accordingly if you are carrying both players.

Is Jacoby Brissett or Patrick Mahomes a better fantasy quarterback in 2026?

Patrick Mahomes outscored Jacoby Brissett by 4.4 PPG in 2025, which gives him the edge heading into 2026. For a week-by-week verdict, DraftCall's AI analyzes matchup quality and recent trends in real time.