James Conner vs Miles Sanders: The Full Breakdown
If you are choosing between James Conner and Miles Sanders for your lineup, you are not alone. James Conner finished the 2025 season at 11.0 PPG for the Arizona Cardinals (14 games), and Miles Sanders averaged 5.7 for the Dallas Cowboys (4 games).
That 5.3-point weekly advantage for James Conner is meaningful but not automatic. Fantasy football is a week-to-week sport, and the answer to "who should I start" often changes based on opponent, recent form, and game environment. Season averages set the baseline; weekly context makes the call.
Both profile as early-down workhorses. James Conner ran for 752 yards and 5 touchdowns; Miles Sanders posted 117 and 1. Goal-line share, red zone touches, and which team is favored are usually the tiebreaker when neither back offers passing-game volume.
One scheduling note: James Conner is off Week 11 and Miles Sanders Week 14. If these two are on your roster, you will need a fill-in running back for both weeks. DraftCall flags bye conflicts so you can plan ahead rather than panic on waivers.
