Head to Head

Updated June 3, 2026 from live stats

Joe Mixon vs Kyren WilliamsWho should you start in 2026 fantasy football?

Joe Mixon is the better fantasy start for 2026, averaging 16.5 PPG to Kyren Williams's 14.4 in 2025. Full head to head breakdown below.

The Bottom Line

Joe Mixon is the better fantasy play this season.

Joe Mixon has the edge, but it is not a runaway. The 2.1-PPG advantage is real (16.5 to 14.4), and Joe Mixon's 12 touchdowns show scoring upside. Kyren Williams is the buy-low candidate if recent production has dipped, because the talent gap is smaller than the numbers suggest.

Moderate confidence: stats favor the leader, but matchup variance could flip this weekly.

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RBHouston Texans#99PPG LEADER

Joe Mixon

PPG

16.5

Games

Rush Yds

1,165

Rush TDs

Rec

Rec Yds

240

Bye

Week 14

RBLos Angeles Rams#11

Kyren Williams

PPG

14.4

Games

Rush Yds

1,252

Rush TDs

Rec

Rec Yds

281

Bye

Week 11

The Edge Chart

Joe Mixon

Kyren Williams

Head to Head

16.5 PPG14.4 PPG

15 GP17 GP

Bye: Week 14Bye: Week 11

Fantasy Tiers

Joe Mixon: Tier 5 (Deep League) RB (ranked #99 at the position). Kyren Williams: Tier 2 (Strong Starter) RB (ranked #11 at the position). Among the top 50 running backs this season, Joe Mixon is producing at 75% of elite pace and Kyren Williams at 65%. That ranking gap means Kyren Williams carries more trade value and a higher draft cost in 2026.

Joe Mixon vs Kyren Williams: The Full Breakdown

Two running backs who will land on plenty of the same rosters in 2026. Joe Mixon (Houston Texans) finished the 2025 season averaging 16.5 fantasy points per game in 15 games. Kyren Williams (Los Angeles Rams) came in at 14.4 PPG over 17 games. The gap is real but not insurmountable with the right matchup.

Joe Mixon carries a 2.1-point PPG advantage from the 2025 season. That baseline matters, but it is one input among several. Matchup difficulty, scoring trends, and injury reports move the needle week to week, which is why the best answer changes depending on when you are asking.

Both profile as early-down workhorses. Joe Mixon ran for 1165 yards and 11 touchdowns; Kyren Williams posted 1252 and 10. Goal-line share, red zone touches, and which team is favored are usually the tiebreaker when neither back offers passing-game volume.

Bye weeks matter for roster construction: Joe Mixon sits Week 14 while Kyren Williams is off Week 11. If you are deciding between the two as a season-long roster hold, the staggered byes actually work in your favor.

Trade Value + Dynasty Outlook

Both are in a similar trade value range. A straight swap would be fair in most leagues, with the tiebreaker going to whichever manager values schedule or bye week more. Dynasty outlook: Joe Mixon (age 27) is approaching the age where RB production historically drops. Sell-high window is open. Kyren Williams (age 25) has not yet hit the RB cliff. High dynasty ceiling if volume holds.

Did You Know?

•Joe Mixon outscored Kyren Williams by a projected 36 total fantasy points over a full 17-game season.
•Kyren Williams played 17 games in 2025 compared to Joe Mixon's 15. That durability gap means Kyren Williams contributed more total fantasy points even before you look at per-game averages.
•Kyren Williams scored 13 total touchdowns in 2025 (0.8 per game), making him one of the more reliable scoring options at running back.
•Kyren Williams caught 36 passes in 2025. Pass-catching backs average 2-3 more PPG in half-PPR than their non-receiving counterparts.

Detailed Stat Breakdown

Joe Mixon vs Kyren Williams: 2025 fantasy football stat comparison in the half-PPR scoring format.
Stat	Joe Mixon	Kyren Williams
PPG (Half-PPR)	16.5	14.4
Games Played	15	17
Total Fantasy Pts (est.)	248	245
Rushing Yards	1,165	1,252
Rush Yds/Game	77.7	73.6
Rushing TDs	11	10
Receptions	32	36
Receiving Yards	240	281
Targets	0	50
Total TDs	12	13
Age	-	25
Experience	-	3 yrs
Bye Week	Week 14	Week 11

Summary

Based on 2025 production, Joe Mixon holds the PPG edge with solid output at 16.5 points per game. Kyren Williams averaged 14.4 PPG. Season averages are a starting point, not the final word. For a full AI analysis factoring matchup quality, recent form, injury impact, and game script, download DraftCall and get a verdict backed by real data.

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Frequently Asked Questions

Should I start Joe Mixon or Kyren Williams in fantasy football?▾

Based on 2025 season averages, Joe Mixon has the edge at 16.5 PPG compared to Kyren Williams's 14.4 PPG. However, the best start depends on weekly matchup, recent form, and injury status. DraftCall's app provides real-time AI-powered verdicts that factor in all of these variables.

How many fantasy points did Joe Mixon and Kyren Williams average in 2025?▾

Joe Mixon averaged 16.5 fantasy points per game (half-PPR) across 15 games in 2025. Kyren Williams averaged 14.4 PPG over 17 games. That is a difference of 2.1 points per game.

When are Joe Mixon and Kyren Williams's bye weeks in 2026?▾

Joe Mixon (HOU) has a bye in Week 14, and Kyren Williams (LAR) has a bye in Week 11. Plan your roster accordingly if you are carrying both players.

Is Joe Mixon or Kyren Williams a better fantasy running back in 2026?▾

Joe Mixon outscored Kyren Williams by 2.1 PPG in 2025, which gives him the edge heading into 2026. For a week-by-week verdict, DraftCall's AI analyzes matchup quality and recent trends in real time.