Head to Head

Updated June 3, 2026 from live stats

Joe Mixon vs Mark AndrewsWho should you start in 2026 fantasy football?

Joe Mixon is the better fantasy start for 2026, averaging 16.5 PPG to Mark Andrews's 6.3 in 2025. Full head to head breakdown below.

The Bottom Line

Joe Mixon is the better fantasy play this season.

Cross-position decisions depend on league format. In half-PPR, Joe Mixon (16.5 PPG) is the higher-floor play. Mark Andrews (6.3 PPG) could win a specific week on touchdown variance. For FLEX spots, lean toward the player with the softer defensive matchup that week rather than defaulting to season averages.

High confidence: stats strongly favor the leader, and the gap is unlikely to close on matchup alone.

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RBHouston Texans#99PPG LEADER

Joe Mixon

PPG

16.5

Games

Rush Yds

1,165

Rush TDs

Rec

Rec Yds

240

Bye

Week 14

TEBaltimore Ravens#27

Mark Andrews

PPG

6.3

Games

Rec

Rec Yds

422

Rec TDs

Targets

Bye

Week 13

The Edge Chart

Joe Mixon

Mark Andrews

Head to Head

16.5 PPG6.3 PPG

15 GP17 GP

Bye: Week 14Bye: Week 13

Fantasy Tiers

Joe Mixon: Tier 5 (Deep League) RB (ranked #99 at the position). Mark Andrews: Tier 4 (Bench/Bye Fill) TE (ranked #27 at the position). Comparing across positions, raw PPG is less useful than positional scarcity. A Tier 5 (Deep League) RB is harder to replace on waivers than a Tier 4 (Bench/Bye Fill) TE in most league formats.

Joe Mixon vs Mark Andrews: The Full Breakdown

Comparing Joe Mixon (RB, Houston Texans) against Mark Andrews (TE, Baltimore Ravens) means weighing two different roles in your fantasy lineup. Joe Mixon averaged 16.5 PPG in 2025 over 15 games, while Mark Andrews posted 6.3 PPG across 17 games.

Cross-position FLEX decisions cannot be made on PPG alone. Positional scarcity, matchup quality, floor versus ceiling, and league scoring format all shift the answer. A 14 PPG tight end in a thin TE week is often worth more than a 16 PPG receiver in a deep WR week, because the opportunity cost on the waiver wire is wildly different.

DraftCall's AI engine weighs all of these signals and returns a verdict with clear reasoning, so you are not cross-referencing four different rankings tabs on a Sunday morning.

Joe Mixon has his bye in Week 14, Mark Andrews in Week 13. Plan your FLEX rotation around those weeks, especially if either player is anchoring your roster.

Trade Value + Dynasty Outlook

If you can acquire Joe Mixon at a discount because your league-mates undervalue running back production, do it. Mark Andrews is a reasonable sell-high candidate if his recent games have spiked above his season average. Dynasty outlook: Joe Mixon (age 27) is approaching the age where RB production historically drops. Sell-high window is open. Mark Andrews (age 30) is in the later years of production. Still a redraft asset, but dynasty value is declining.

Did You Know?

•Joe Mixon outscored Mark Andrews by a projected 173 total fantasy points over a full 17-game season.
•Mark Andrews played 17 games in 2025 compared to Joe Mixon's 15. That durability gap means Mark Andrews contributed more total fantasy points even before you look at per-game averages.
•Joe Mixon scored 12 total touchdowns in 2025 (0.8 per game), making him one of the more reliable scoring options at running back.
•Mark Andrews caught 48 passes in 2025. Pass-catching backs average 2-3 more PPG in half-PPR than their non-receiving counterparts.

Detailed Stat Breakdown

Joe Mixon vs Mark Andrews: 2025 fantasy football stat comparison in the half-PPR scoring format.
Stat	Joe Mixon	Mark Andrews
PPG (Half-PPR)	16.5	6.3
Games Played	15	17
Total Fantasy Pts (est.)	248	107
Rushing Yards	1,165	48
Rush Yds/Game	77.7	2.8
Rushing TDs	11	1
Receptions	32	48
Receiving Yards	240	422
Targets	0	70
Total TDs	12	6
Age	-	30
Experience	-	7 yrs
Bye Week	Week 14	Week 13

Summary

Based on 2025 production, Joe Mixon holds the PPG edge with solid output at 16.5 points per game. Mark Andrews averaged 6.3 PPG. Season averages are a starting point, not the final word. For a full AI analysis factoring matchup quality, recent form, injury impact, and game script, download DraftCall and get a verdict backed by real data.

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Frequently Asked Questions

Should I start Joe Mixon or Mark Andrews in fantasy football?▾

Based on 2025 season averages, Joe Mixon has the edge at 16.5 PPG compared to Mark Andrews's 6.3 PPG. However, the best start depends on weekly matchup, recent form, and injury status. DraftCall's app provides real-time AI-powered verdicts that factor in all of these variables.

How many fantasy points did Joe Mixon and Mark Andrews average in 2025?▾

Joe Mixon averaged 16.5 fantasy points per game (half-PPR) across 15 games in 2025. Mark Andrews averaged 6.3 PPG over 17 games. That is a difference of 10.2 points per game.

When are Joe Mixon and Mark Andrews's bye weeks in 2026?▾

Joe Mixon (HOU) has a bye in Week 14, and Mark Andrews (BAL) has a bye in Week 13. Plan your roster accordingly if you are carrying both players.