Head to Head

Updated June 3, 2026 from live stats

Joe Mixon vs Omarion HamptonWho should you start in 2026 fantasy football?

Joe Mixon is the better fantasy start for 2026, averaging 16.5 PPG to Omarion Hampton's 13.3 in 2025. Full head to head breakdown below.

The Bottom Line

Joe Mixon is the better fantasy play this season.

Joe Mixon is the better play on a neutral week. 16.5 PPG with 1,405 yards gives a reliable baseline. Omarion Hampton at 13.3 PPG is not far behind and could win specific weeks where matchup and game script align. Draft Joe Mixon higher, but do not fade Omarion Hampton entirely.

Moderate confidence: stats favor the leader, but matchup variance could flip this weekly.

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RBHouston Texans#99PPG LEADER

Joe Mixon

PPG

16.5

Games

Rush Yds

1,165

Rush TDs

Rec

Rec Yds

240

Bye

Week 14

RBLos Angeles Chargers#15

Omarion Hampton

PPG

13.3

Games

Rush Yds

545

Rush TDs

Rec

Rec Yds

192

Bye

Week 7

The Edge Chart

Joe Mixon

Omarion Hampton

Head to Head

16.5 PPG13.3 PPG

15 GP9 GP

Bye: Week 14Bye: Week 7

Fantasy Tiers

Joe Mixon: Tier 5 (Deep League) RB (ranked #99 at the position). Omarion Hampton: Tier 3 (Flex/Starter) RB (ranked #15 at the position). Among the top 50 running backs this season, Joe Mixon is producing at 75% of elite pace and Omarion Hampton at 60%. That ranking gap means Omarion Hampton carries more trade value and a higher draft cost in 2026.

Joe Mixon vs Omarion Hampton: The Full Breakdown

If you are choosing between Joe Mixon and Omarion Hampton for your lineup, you are not alone. Joe Mixon finished the 2025 season at 16.5 PPG for the Houston Texans (15 games), and Omarion Hampton averaged 13.3 for the Los Angeles Chargers (9 games).

That 3.2-point weekly advantage for Joe Mixon is meaningful but not automatic. Fantasy football is a week-to-week sport, and the answer to "who should I start" often changes based on opponent, recent form, and game environment. Season averages set the baseline; weekly context makes the call.

Both profile as early-down workhorses. Joe Mixon ran for 1165 yards and 11 touchdowns; Omarion Hampton posted 545 and 4. Goal-line share, red zone touches, and which team is favored are usually the tiebreaker when neither back offers passing-game volume.

One scheduling note: Joe Mixon is off Week 14 and Omarion Hampton Week 7. If these two are on your roster, you will need a fill-in running back for both weeks. DraftCall flags bye conflicts so you can plan ahead rather than panic on waivers.

Trade Value + Dynasty Outlook

Joe Mixon is a buy in trades where the other manager is chasing upside at a different position. Omarion Hampton is a hold unless you can flip him for a positional upgrade elsewhere on your roster. Dynasty outlook: Joe Mixon (age 27) is approaching the age where RB production historically drops. Sell-high window is open. Omarion Hampton (age 23) has not yet hit the RB cliff. High dynasty ceiling if volume holds.

Did You Know?

•Joe Mixon outscored Omarion Hampton by a projected 54 total fantasy points over a full 17-game season.
•Joe Mixon played 15 games in 2025 compared to Omarion Hampton's 9. That durability gap means Joe Mixon contributed more total fantasy points even before you look at per-game averages.
•Joe Mixon scored 12 total touchdowns in 2025 (0.8 per game), making him one of the more reliable scoring options at running back.
•Omarion Hampton caught 32 passes in 2025. Pass-catching backs average 2-3 more PPG in half-PPR than their non-receiving counterparts.

Detailed Stat Breakdown

Joe Mixon vs Omarion Hampton: 2025 fantasy football stat comparison in the half-PPR scoring format.
Stat	Joe Mixon	Omarion Hampton
PPG (Half-PPR)	16.5	13.3
Games Played	15	9
Total Fantasy Pts (est.)	248	120
Rushing Yards	1,165	545
Rush Yds/Game	77.7	60.6
Rushing TDs	11	4
Receptions	32	32
Receiving Yards	240	192
Targets	0	35
Total TDs	12	5
Age	-	23
Bye Week	Week 14	Week 7

Summary

The 2025 numbers favor Joe Mixon at 16.5 PPG, 3.2 points per game above Omarion Hampton's 13.3. But season stats only tell part of the story. DraftCall's AI factors in weekly matchup, recent form, and injury status to give you a verdict that updates with the latest data.

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Frequently Asked Questions

Should I start Joe Mixon or Omarion Hampton in fantasy football?▾

Based on 2025 season averages, Joe Mixon has the edge at 16.5 PPG compared to Omarion Hampton's 13.3 PPG. However, the best start depends on weekly matchup, recent form, and injury status. DraftCall's app provides real-time AI-powered verdicts that factor in all of these variables.

How many fantasy points did Joe Mixon and Omarion Hampton average in 2025?▾

Joe Mixon averaged 16.5 fantasy points per game (half-PPR) across 15 games in 2025. Omarion Hampton averaged 13.3 PPG over 9 games. That is a difference of 3.2 points per game.

When are Joe Mixon and Omarion Hampton's bye weeks in 2026?▾

Joe Mixon (HOU) has a bye in Week 14, and Omarion Hampton (LAC) has a bye in Week 7. Plan your roster accordingly if you are carrying both players.

Is Joe Mixon or Omarion Hampton a better fantasy running back in 2026?▾

Joe Mixon outscored Omarion Hampton by 3.2 PPG in 2025, which gives him the edge heading into 2026. For a week-by-week verdict, DraftCall's AI analyzes matchup quality and recent trends in real time.