Joe Mixon vs Zach Charbonnet: The Full Breakdown
Deciding between Joe Mixon and Zach Charbonnet is a common lineup dilemma for fantasy managers. The Houston Texans running back put up 16.5 PPG in 2025 over 15 games; Zach Charbonnet of the Seattle Seahawks averaged 10.7 in 16. A 5.8-point margin that could shift on any given week.
The per-game difference of 5.8 points favors Joe Mixon, though savvy managers know that gap can shrink or widen depending on the weekly slate. Defensive matchup, recent scoring trends, and health status all shift the calculus from one running back to the other.
Both profile as early-down workhorses. Joe Mixon ran for 1165 yards and 11 touchdowns; Zach Charbonnet posted 730 and 12. Goal-line share, red zone touches, and which team is favored are usually the tiebreaker when neither back offers passing-game volume.
One scheduling note: Joe Mixon is off Week 14 and Zach Charbonnet Week 11. If these two are on your roster, you will need a fill-in running back for both weeks. DraftCall flags bye conflicts so you can plan ahead rather than panic on waivers.
