Jonathan Taylor vs Kyren Williams: Who Should You Start?
Deciding between Jonathan Taylor and Kyren Williams is a common lineup dilemma for fantasy managers. The Indianapolis Colts running back put up 20.0 PPG in 2025 over 17 games; Kyren Williams of the Los Angeles Rams averaged 14.4 in 17. A 5.6-point margin that could shift on any given week.
The per-game difference of 5.6 points favors Jonathan Taylor, though savvy managers know that gap can shrink or widen depending on the weekly slate. Defensive matchup, recent scoring trends, and health status all shift the calculus from one running back to the other.
Jonathan Taylor is the receiving back in this matchup, turning 46 targets into 378 yards, while Kyren Williams profiles as a more traditional rusher with 1252 rushing yards and 10 touchdowns. In PPR and half-PPR formats Jonathan Taylor carries the higher weekly floor. In standard leagues the gap tightens considerably.
One scheduling note: Jonathan Taylor is off Week 14 and Kyren Williams Week 6. If these two are on your roster, you will need a fill-in running back for both weeks. DraftCall flags bye conflicts so you can plan ahead rather than panic on waivers.