Jonathan Taylor vs TreVeyon Henderson: Who Should You Start?
There is a real production gap between these two running backs. Jonathan Taylor (Indianapolis Colts) averaged 20.0 PPG over 17 games in 2025, outscoring TreVeyon Henderson (New England Patriots, 11.1 PPG) by 8.9 points per week. That separation would need a significant matchup swing to overcome.
Jonathan Taylor carries a 8.9-point PPG advantage from the 2025 season. That baseline matters, but it is one input among several. Matchup difficulty, scoring trends, and injury reports move the needle week to week, which is why the best answer changes depending on when you are asking.
Jonathan Taylor is the receiving back in this matchup, turning 46 targets into 378 yards, while TreVeyon Henderson profiles as a more traditional rusher with 911 rushing yards and 9 touchdowns. In PPR and half-PPR formats Jonathan Taylor carries the higher weekly floor. In standard leagues the gap tightens considerably.
One thing to note: both players share a Week 14 bye. That means you need a backup plan at running back for that week, especially if one of these two is your starter.