Omarion Hampton vs Samaje Perine: The Full Breakdown
The numbers tell a clear story here. Omarion Hampton put up 13.3 fantasy points per game for the Los Angeles Chargers in 2025, while Samaje Perine managed 6.5 across 15 games with the Kansas City Chiefs. A 6.8-point weekly edge is substantial at the running back position.
Omarion Hampton carries a 6.8-point PPG advantage from the 2025 season. That baseline matters, but it is one input among several. Matchup difficulty, scoring trends, and injury reports move the needle week to week, which is why the best answer changes depending on when you are asking.
Both profile as early-down workhorses. Omarion Hampton ran for 545 yards and 4 touchdowns; Samaje Perine posted 285 and 2. Goal-line share, red zone touches, and which team is favored are usually the tiebreaker when neither back offers passing-game volume.
Bye weeks matter for roster construction: Omarion Hampton sits Week 7 while Samaje Perine is off Week 6. If you are deciding between the two as a season-long roster hold, the staggered byes actually work in your favor.
