Omarion Hampton vs Tyjae Spears: Who Should You Start?
There is a real production gap between these two running backs. Omarion Hampton (Los Angeles Chargers) averaged 13.3 PPG over 9 games in 2025, outscoring Tyjae Spears (Tennessee Titans, 6.9 PPG) by 6.4 points per week. That separation would need a significant matchup swing to overcome.
That 6.4-point weekly advantage for Omarion Hampton is meaningful but not automatic. Fantasy football is a week-to-week sport, and the answer to "who should I start" often changes based on opponent, recent form, and game environment. Season averages set the baseline; weekly context makes the call.
Tyjae Spears is the receiving back in this matchup, turning 45 targets into 264 yards, while Omarion Hampton profiles as a more traditional rusher with 545 rushing yards and 4 touchdowns. In PPR and half-PPR formats Tyjae Spears carries the higher weekly floor. In standard leagues the gap tightens considerably.
Both share a Week 5 bye, which matters for roster construction. If you are stacking running backs this deep on your bench, plan your replacement running back early.
