Saquon Barkley vs TreVeyon Henderson: Who Should You Start?
If you are choosing between Saquon Barkley and TreVeyon Henderson for your lineup, you are not alone. Saquon Barkley finished the 2025 season at 13.4 PPG for the Philadelphia Eagles (16 games), and TreVeyon Henderson averaged 11.1 for the New England Patriots (17 games).
That 2.3-point weekly advantage for Saquon Barkley is meaningful but not automatic. Fantasy football is a week-to-week sport, and the answer to "who should I start" often changes based on opponent, recent form, and game environment. Season averages set the baseline; weekly context makes the call.
Both profile as early-down workhorses. Saquon Barkley ran for 1140 yards and 7 touchdowns; TreVeyon Henderson posted 911 and 9. Goal-line share, red zone touches, and which team is favored are usually the tiebreaker when neither back offers passing-game volume.
Saquon Barkley has his bye in Week 5, and TreVeyon Henderson rests in Week 14. Managers rostering both need waiver wire depth at running back for those two weeks, and that is exactly the kind of planning DraftCall's matchup engine surfaces automatically so you are not scrambling on a Sunday morning.
