The San Francisco 49ers play in the NFC West and compete in the NFC conference. This page tracks the full fantasy-relevant roster for the 2026 NFL season, ranked by 2025 per-game production and refreshed daily from live NFL stats. If a player is on the active roster and inside the top tier at their position, you will find them here.
Across the four main fantasy positions, we currently rank 7 San Francisco 49ers players inside the 2026 top tiers. 2 quarterbacks, 1 running back, 2 wide receivers, 2 tight ends. Christian McCaffrey leads the group with 21.5 fantasy points per game in 2025 and is the most likely anchor of any San Francisco 49ers-heavy fantasy stack.
The San Francisco 49ers are on bye in Week 9, which means every fantasy manager rostering one of their players needs bench depth or a waiver-wire plan locked in for that week.
DraftCall's AI matchup engine lets you pit any San Francisco 49ers player against any other NFL starter in seconds, factoring in matchup, recent form, and scoring format. Use this page as your starting point for weekly start or sit decisions involving the 49ers.
