Bo Nix vs Brock Purdy: Who Should You Start?
If you are choosing between Bo Nix and Brock Purdy for your lineup, you are not alone. Bo Nix finished the 2025 season at 18.6 PPG for the Denver Broncos (17 games), and Brock Purdy averaged 20.8 for the San Francisco 49ers (9 games).
That 2.2-point weekly advantage for Brock Purdy is meaningful but not automatic. Fantasy football is a week-to-week sport, and the answer to "who should I start" often changes based on opponent, recent form, and game environment. Season averages set the baseline; weekly context makes the call.
Both lean on arm talent and offensive scheme as traditional pocket passers. Bo Nix threw for 3931 yards and 25 touchdowns, while Brock Purdy posted 2167 yards and 20 scores. Volume, red zone efficiency, and game script are the key week-to-week differentiators when neither carries rushing upside.
One scheduling note: Bo Nix is off Week 14 and Brock Purdy Week 9. If these two are on your roster, you will need a fill-in quarterback for both weeks. DraftCall flags bye conflicts so you can plan ahead rather than panic on waivers.
