Christian McCaffrey vs Zack Moss: The Full Breakdown
The numbers tell a clear story here. Christian McCaffrey put up 21.5 fantasy points per game for the San Francisco 49ers in 2025, while Zack Moss managed 10.0 across 14 games with the Cincinnati Bengals. A 11.5-point weekly edge is substantial at the running back position.
A 11.5-PPG gap gives Christian McCaffrey the edge on paper, but paper does not account for Thursday night matchups, weather games, or a star defender returning from injury. The real question is not who was better in 2025, but who is the better start this specific week.
Christian McCaffrey is the receiving back in this matchup, turning 102 targets into 924 yards, while Zack Moss profiles as a more traditional rusher with 685 rushing yards and 5 touchdowns. In PPR and half-PPR formats Christian McCaffrey carries the higher weekly floor. In standard leagues the gap tightens considerably.
Bye weeks matter for roster construction: Christian McCaffrey sits Week 8 while Zack Moss is off Week 12. If you are deciding between the two as a season-long roster hold, the staggered byes actually work in your favor.
