De'Von Achane vs Dylan Sampson: Who Should You Start?
There is a real production gap between these two running backs. De'Von Achane (Miami Dolphins) averaged 18.1 PPG over 16 games in 2025, outscoring Dylan Sampson (Cleveland Browns, 4.7 PPG) by 13.4 points per week. That separation would need a significant matchup swing to overcome.
De'Von Achane carries a 13.4-point PPG advantage from the 2025 season. That baseline matters, but it is one input among several. Matchup difficulty, scoring trends, and injury reports move the needle week to week, which is why the best answer changes depending on when you are asking.
De'Von Achane is the receiving back in this matchup, turning 67 targets into 488 yards, while Dylan Sampson profiles as a more traditional rusher with 175 rushing yards and undefined touchdowns. In PPR and half-PPR formats De'Von Achane carries the higher weekly floor. In standard leagues the gap tightens considerably.
One scheduling note: De'Von Achane is off Week 6 and Dylan Sampson Week 10. If these two are on your roster, you will need a fill-in running back for both weeks. DraftCall flags bye conflicts so you can plan ahead rather than panic on waivers.
