De'Von Achane vs Zonovan Knight: Who Should You Start?
There is a real production gap between these two running backs. De'Von Achane (Miami Dolphins) averaged 18.1 PPG over 16 games in 2025, outscoring Zonovan Knight (Arizona Cardinals, 6.8 PPG) by 11.3 points per week. That separation would need a significant matchup swing to overcome.
The per-game difference of 11.3 points favors De'Von Achane, though savvy managers know that gap can shrink or widen depending on the weekly slate. Defensive matchup, recent scoring trends, and health status all shift the calculus from one running back to the other.
De'Von Achane is the receiving back in this matchup, turning 67 targets into 488 yards, while Zonovan Knight profiles as a more traditional rusher with 269 rushing yards and 4 touchdowns. In PPR and half-PPR formats De'Von Achane carries the higher weekly floor. In standard leagues the gap tightens considerably.
One scheduling note: De'Von Achane is off Week 6 and Zonovan Knight Week 11. If these two are on your roster, you will need a fill-in running back for both weeks. DraftCall flags bye conflicts so you can plan ahead rather than panic on waivers.
