Kyler Murray vs Patrick Mahomes: Who Should You Start?
If you are choosing between Kyler Murray and Patrick Mahomes for your lineup, you are not alone. Kyler Murray finished the 2025 season at 16.2 PPG for the Minnesota Vikings (5 games), and Patrick Mahomes averaged 21.2 for the Kansas City Chiefs (14 games).
That 5.0-point weekly advantage for Patrick Mahomes is meaningful but not automatic. Fantasy football is a week-to-week sport, and the answer to "who should I start" often changes based on opponent, recent form, and game environment. Season averages set the baseline; weekly context makes the call.
Patrick Mahomes offers meaningful rushing upside with 422 yards on the ground in 2025, which separates his floor from a pocket passer like Kyler Murray (962 passing yards, 6 touchdowns). In games where the passing matchup looks ugly, that rushing production can be the entire difference on a start/sit call.
Both share a Week 6 bye, which matters for roster construction. If you are stacking quarterbacks this deep on your bench, plan your replacement quarterback early.
